FLCCC says to take Ivermectin with a meal for best absorption, but just about anywhere else (through internet search) says take on empty stomach. Does anyone have any research showing which way would be the most effective way for taking IVM?
FLCCC says to take Ivermectin with a meal for best absorption, but just about anywhere else (through internet search) says take on empty stomach. Does anyone have any research showing which way would be the most effective way for taking IVM?
Ivermectin should be taken on an empty stomach only if you are treating some parasitic infections. Otherwise it is much more potent when taken with a fatty meal. I read this recently on substack but cannot remember where.
Billions of people take this all the time in countries other than 1st world countries like us. All kinds of living conditions locations, etc. I doubt there is much of an issue about this.
The issue is around obtaining best (maximum) absorption. Some meds/supplements need fats for best absorption, some donтАЩt. So, is there research that I am not readily finding that indicates which is best way for taking it. No doubt people around the world just toss it down however without problem, but are they getting maximum benefits.
I agree. I take my D with a meal containing fat. Plus others. IтАЩve just never seen this addressed with IVM and I have read ALOT about it. So clarification would be nice. Cheers.
I read some document (can't remember what/where) that if you take ivm with a fatty meal, you get 2.5x the absorbtion into your blood stream compared to taking it on an empty stomach. If you take it on an empty stomach, there is more left behind to do its work on your gut parasites. So WHY you take it dictates HOW you should take it.
Thanks! Makes sense that way too. I did recently run across this in a paper -
"the high lipid solubility of ivermectin resulting in it being widely distributed throughout the body. Following oral administration, mean peak plasma concentration occurs approximately 4тАЙh after dosing, a second peak at 6тАУ12тАЙh probably arising because of enterohepatic recycling of the drug, with the plasma half-life of ivermectin being around 12тАЙh"
The high lipid solubility certainly seems to suggest taking with a meal
Thanks. I think it makes sense to take with food and fats for general purposes. For treating internal parasites it does make sense to use on empty stomach though. We тАЬstarveтАЭ our goats before we treat them with IVM or other anthelmintics...they donтАЩt approve of having to do without a meal though ЁЯШВ
FLCCC says to take Ivermectin with a meal for best absorption, but just about anywhere else (through internet search) says take on empty stomach. Does anyone have any research showing which way would be the most effective way for taking IVM?
Ivermectin should be taken on an empty stomach only if you are treating some parasitic infections. Otherwise it is much more potent when taken with a fatty meal. I read this recently on substack but cannot remember where.
Billions of people take this all the time in countries other than 1st world countries like us. All kinds of living conditions locations, etc. I doubt there is much of an issue about this.
The issue is around obtaining best (maximum) absorption. Some meds/supplements need fats for best absorption, some donтАЩt. So, is there research that I am not readily finding that indicates which is best way for taking it. No doubt people around the world just toss it down however without problem, but are they getting maximum benefits.
Ben Fen had a good post on this. Taken with butter, olive oil or peanut butter is best for absorption
Rick, my bottle of pills says to take with food.
I agree. I take my D with a meal containing fat. Plus others. IтАЩve just never seen this addressed with IVM and I have read ALOT about it. So clarification would be nice. Cheers.
I suspect that it is slightly better to take it with at least a little food, true for most things....
I read some document (can't remember what/where) that if you take ivm with a fatty meal, you get 2.5x the absorbtion into your blood stream compared to taking it on an empty stomach. If you take it on an empty stomach, there is more left behind to do its work on your gut parasites. So WHY you take it dictates HOW you should take it.
Thanks! Makes sense that way too. I did recently run across this in a paper -
"the high lipid solubility of ivermectin resulting in it being widely distributed throughout the body. Following oral administration, mean peak plasma concentration occurs approximately 4тАЙh after dosing, a second peak at 6тАУ12тАЙh probably arising because of enterohepatic recycling of the drug, with the plasma half-life of ivermectin being around 12тАЙh"
The high lipid solubility certainly seems to suggest taking with a meal
Ditto this question.
I have done both and prefer to take it with fatty food or my fish oil.
My prescription said on an empty stomach. I think itтАЩs better absorbed with fatty foods. Just my opinion and I have no proof.
Thanks. I think it makes sense to take with food and fats for general purposes. For treating internal parasites it does make sense to use on empty stomach though. We тАЬstarveтАЭ our goats before we treat them with IVM or other anthelmintics...they donтАЩt approve of having to do without a meal though ЁЯШВ