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My question is, does IVM still work against the newer varieties? (Clades?)

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Unlike targeted therapies like monoclonal antibodies or the purported intention of the Mod RNA vaccines that target very specific antigens that can evolve very quickly rendering targeted treatments obsolete, IVM, HCQ, Flavonoids, Antihelmintics are host adaptive therapeutics making the overall cellular environment unfriendly for pathogens ie raising cellular PH, thus work against a wide variety of pathogens.

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